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Agents in this group include peroxisome proliferator-activated receptor agonists (e.g., pioglitazone, elafibranor, saroglitazar), bile acid-farnesoid X receptor axis regulators (obeticholic acid), de novo lipogenesis inhibitors (aramchol, NDI-010976), and fibroblast growth factor 21/19 analogs

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The 2.5 g dosage can be indicated in dialysis patients over 1 year

Do not use if you have been diagnosed with cardiovascular disease, cardiovascular disorders, low blood pressure or an increased risk of non-arteritic anterior ischemic optic neuropathy (NAION)

we dont adopt new treatments until they have cleared every regulatory hurdle and established a robust safety profile through documented protocols and audit-ready processes